Preheat the oven to 375°F.
In a large mixing bowl, combine the ground beef, breadcrumbs, chopped onion, garlic, eggs, milk, ketchup, Worcestershire sauce, salt, pepper, parsley, thyme, and oregano.
Mix gently with clean hands or a spoon until everything is just combined, be careful not to overmix.
Lightly grease your Dutch oven with cooking spray or a small amount of olive oil.
Shape the meat mixture into a loaf and place it directly in the Dutch oven.
Spread a layer of ketchup over the top of the loaf.
Cover with the lid and bake for 40 minutes.
Remove the lid and bake uncovered for an additional 15–20 minutes, or until the internal temperature reaches 160°F and the top is glazed.
Let the meatloaf rest for 10 minutes before slicing and serving.